As a widely used inorganic material, silicon dioxide is also a very useful pharmaceutical excipient in the pharmaceutical field. The excipient silica structure formula mSiO2·nH2O is a white powder with good fluidity, high purity and no pollution. It has the characteristics of small particle size, large specific surface area and many pores. At the same time, the silicon hydroxyl group distributed on the surface makes it have good adsorption performance. The addition of pharmaceutical excipients silica can effectively improve the quality and performance of pharmaceutical preparations, especially tablets, and greatly improve the market competitiveness of drugs.